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The authors present an important set of data implicating ETFDH as an epigenetically suppressed gene in cancer with tumor suppressive functions. The evidence is solid, with the authors demonstrating ...
The White House Correspondents' Association hosted its annual dinner in Washington, DC to recognize various journalists … Former White House Press Secretary Sean Spicer and former CNN Washington ...
NBC News Senior Congressional reporter Scott Wong previews a key week in the GOP budget reconciliation process and Middle East Institute Paul Salem discusses President Trump's Middle East trip ...
Treatment with an mTOR inhibitor in 6-month-old TRGL/Q175 mice normalized lysosome numbers, alleviated aggresome pathology, and reduced mHTT, p62, and ubiquitin levels. These findings suggest that ...
Major Finding: Dietary ω-6 linoleic acid (LA) promotes oncogenic mTOR signaling in triple-negative breast cancer (TNBC). Concept: TNBCs express the fatty acid binding protein FABP5, which senses ω-6 ...
Two important factors in relapse are MYCN amplification and intratumoral heterogeneity. MYCN, a transcription factor of the MYC family, is amplified in about 40% of high-risk NB cases and is ...
Circular RNAs (circRNAs) have been gradually revealed to regulate the progression of heart disease in depth, showing their clinical significance. However, a mass of cardiac circRNAs still has not been ...
In recent years, the incidence and mortality of pancreatic cancer (PC) are increasing year by year. The highly heterogeneous nature of PC, its strong immune escape ability and easy metastasis make it ...