Actin can be found in two forms, monomeric (G-actin) and filamentous (F-actin). The latter forms filaments that are essential for maintaining cell structure and many other functions. The assembly ...

Following expression, purification, and removal of linker and thymosin β4 tag sequences, the p.E334Q monomers show normal integration into linear and branched actin filaments. The mutation does not ...

Actin regulators include actin-monomer-binding proteins, Wiskott-Aldrich syndrome (WAS) family of proteins, nucleation proteins, actin filament polymerases and severing proteins. This group of ...

Actin exists in monomeric form, but like Lego bricks, different types of filamentous structures can be built from actin monomers in cells. Actin filaments are organized in cells in a way that ...

"That's the fast end. The loose connection within the actin polymer allows incoming actin monomers to have access to a binding site, such that it can make a new connection quickly and the ...

The domains are separated by a deep cleft (Figure 1A). The actin monomer is rather flat and fits into a “parallelepiped” with dimensions of 55 Å × 55 Å × 35 Å. A list of 155 protein structures of ...

They built an extensive simulation of Dip1-induced Arp2/3 nucleation, which shows that the ability of Wsp1 to provide the first actin monomer(s) of the newly nucleated filament is part of the ...

The filaments assemble from actin monomers with a bound ATP. After polymerization, actin rapidly hydrolyzes the bound ATP and slowly dissociates the γ-phosphate. ADP-actin filaments then disassemble ...

Cofilin encourages depolymerization by promoting dissociation of actin monomers from the actin chain. Detection can be achieved using one of two antibodies (Anti-Cofilin antibody or its phospho S3 ...

The assembly of this cytoskeleton is controlled at many levels including globular actin monomers (G-protein) undergoing reversible polymerization into actin polymers and the superorganization of ...

Polymerase activity of WASP‐family proteins arises from the recruitment of actin monomers and profilin‐actin complexes to surfaces containing a high density of WASP‐family proteins. Most actin ...