Scientists have unlocked new details on important receptor proteins—promising targets for the creation of novel drugs for ...

A new lipid-based pathway essential for memory formation has been discovered by University of Queensland researchers—a ...

The well-studied NF-κB signaling system is a key mediator of the inflammatory response. Large-scale sequencing studies in ...

In a study published in Science Advances, University of Alabama at Birmingham researchers led by Kasey Brida and Jeremy Day, ...

Emerging evidence suggests that lycopene—a natural plant extract—may have antidepressant properties. New research in Food Science & Nutrition reveals the mechanisms behind its antidepressant ...

The term psychoplastogen refers to a class of small molecules that can rapidly induce structural and functional neural plasticity. Plasticity refers to the brain’s ability to reorganize itself ...

Using a common model for PSD, these studies collectively implicate the BDNF-TrkB signaling pathway and the hippocampus as a target for nutraceutical treatments. Because of the prevalence of poststroke ...

From the perspective of the identified GSK3β/BDNF pathway, these findings demonstrated for the first time that alumina NPs exposure can be a risk factor for prefrontal neuronal and cognitive functions ...

The shame rats were separately housed. For specifically blocking the BDNF signaling pathway, chicken anti-BDNF antibody (Cat#ARG65673, Arigo Biolaboratories, Shanghai, China) was ...

The brain-derived neurotrophic factor/tropomyosin receptor kinase B/cAMP response element-binding protein (BDNF/TrkB/CREB) signaling pathway is a critical therapeutic target for inducing adult ...

Our studies suggest that BDNF/TrkB.T1 signaling is a novel unexplored pathway in the role of astrocytes in synapse development. Given the role of aberrant synapse development in neurological ...