Monocytes were cultured with M‐CSF ... clone H194‐112), anti‐CD226 PE (Biolegend, clone 10E5), anti‐CD11b PE da594 (BD Bioscience, clone M1/70), anti‐CD117 PE dazzle594 (Biolegend, clone 2B8), ...

We also put ready-to-use lysis solutions to the test as we analyze the monocyte activation state by detecting the conformational change of the CD11b/CD18 receptor (macrophage-1 antigen, Mac-1). The ...

The profiling also showed a significant decrease in CCL2 levels and a concomitant reduction in Ly6C hi monocytes in circulation in both groups. These findings suggest that positive allosteric ...

We examined markers of monocyte and neutrophil function and activation (CD11b (activation), TLR-4 expression (LPS recognition), and ROI production (function)) serially over the first week of life ...

Generations of evolutionary pressure have honed a human immune system that is well poised to combat infectious challenges. However, the very same system can turn against us when it is activated by ...

Methods and Results— Human monocytes were isolated from whole blood followed by assessment of CD11b activation/expression and cell adhesion under shear-flow. HDL caused a dose-dependent reduction in ...

To examine the role of monocytes/macrophages in atherosclerosis, we developed CD11b–diphtheria toxin (DT) receptor (DTR) transgenic mice, whereby administration of DT selectively kills ...

We tested the hypothesis that systemic monocyte activation is associated with changes in adipose tissue and skeletal muscle metabolism. In 17 obese hypertensive patients, we assessed CD11b expression ...

Monocytes can adhere to and move across the apical surfaces of endothelial cells with CD11a-CD18, CD11b-CD18 and CD49d-CD29 integrins 5. By activating endothelial cells with interleukin 1β (IL ...

Monocyte chemoattractant protein-1 (MCP-1) stimulates the formation of a collateral circulation on arterial occlusion. The present study served to determine whether these proarteriogenic properties of ...