Our results demonstrate that apigenin activates the c-KIT/Raf/mitogen-activated protein kinase (MAPK)/CREB signalling cascade, upregulates MITF expression, and enhances melanin production. These ...

March is traditionally a busy time for real estate resales in Calgary, but this March saw dampening demand compared with last year, indicating a market leveling off from its frenzied heights in re ...

This important study investigates the molecular mechanisms by which the p53 isoforms Δ133p53α and Δ160p53α exert dominant-negative effects on full-length p53 (FLp53). Through a combination of ...

This important revised manuscript presents compelling findings by delineating two molecularly distinct liver cancer subtypes through comprehensive multi-omics integration and constructing a rigorously ...

The expansion of CAG trinucleotide repeats located in the coding sequence (CDS) of various human genes is associated with the development of neurodegenerative disorders (NDs), including Huntington’s ...