Germ-free and gnotobiotic mice Germ-free mice are completely devoid of any microorganism. Upon inoculation with a pure culture or pre-defined cocktail of microbes, gnotobiotic mice can be generated in ...

Using anaerobic incubation and a gnotobiotic mouse model, they confirmed the role of these microbes in TMA/TMAO production. Finally, researchers developed a qPCR-based method to quantify fecal ...

Called the UB Microbiome Center Gnotobiotic Animal Research Facility, it will train scientists in how to use gnotobiotic (germ-free) mice for research and provide a safe and effective space for ...

The team then causally linked the carcinogen biotransformation to specific bacteria using bacterial culture collections and gnotobiotic mouse models. The researchers analyzed over 500 bacteria to ...

next the team set out to see if this strain could colonize a model of cow’s milk allergy in gnotobiotic mice, which are born germ-free and then engrafted with certain microbes to enable research.

Using a tractable gnotobiotic mouse model and custom diet, we highlight the powerful potential to manipulate the microbiome and immunity during early life, which may have important implications for ...

The current paper, published in the journal Nature Communications, made use of gnotobiotic mouse models, along with GFMM and specific pathogen-free mice (SPF). The gnotobiotic mice (OMM12 ...

A new study finds male mice more unpredictable than females, challenging century-old assumptions used to exclude females from research because of their hormones. By Azeen Ghorayshi For decades ...

Design High-fat high-sucrose diet-fed GF mice underwent FMT-PAC colonisation in sterile individual positive flow ventilated cages under rigorous housing conditions and then maintained for 8 weeks ...