These findings provide a potential explanation for the evolution of the unique HIV capsid structure: its conical shape might be necessary to break the nuclear pore complex and to complete the import ...

Scientists have revealed a rapid movement made by a small molecule called a glycoprotein on the surface of HIV, which happens while the virus ... Researchers have long been trying to stabilize the ...

The role of the structure and organization of the host genome in HIV-1 infection is not well understood. Using a cell culture model based on brain immune microglia cells, an international research ...

"Characterizing the structure of HIV RT was a critical turning point in ... Repetitive elements in the genome such as HERV-K are frequently overexpressed in cancer and elicit biological viral ...

“But the viral genome from HIV is made in small amounts ... “Now that we understand more about the structure of the RNA, we could develop therapeutics, whether they be small molecules or other new ...

The capsid shell that surrounds the viral genome of HIV could offer another targeting strategy, and researchers have now deciphered its complex structure. With cutting edge tools, scientists built a ...

HIV has its RNA genome encapsulated inside a conical-shaped capsid. As well as offering protection from host innate immune responses during the early stage of infection this capsid plays essential ...

A new technique using electron tomography and subtomogram averaging at Diamond's electron Bio-Imaging Centre (eBIC), has solved the structure ... virus (HIV) is a retrovirus; its RNA genome ...

A new technique using electron tomography and subtomogram averaging at Diamond’s electron Bio-Imaging Centre (eBIC), has solved the structure ... (HIV) is a retrovirus which has its RNA genome ...

Researchers can also use the structure to design chemicals that can interact with the protein and change its function, something that has led to therapies for various cancers and HIV. Normally ...

Left: Structure of the Human Immunodeficiency Virus (HIV). Note the envelope protein that protects the virus against immunological detection and the small genome consisting of two short strands of ...