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Durvalumab (Imfinzi) is a PD-L1–blocking antibody that has 3 indications for non–small cell lung cancer (NSCLC). February ...
In the trial, 948 patients were randomized to receive a 1500mg fixed dose of IMFINZI plus FLOT chemotherapy or placebo plus FLOT chemotherapy every four weeks for two cycles prior to surgery.
Adding perioperative durvalumab (Imfinzi) to FLOT chemotherapy significantly improved event-free survival (EFS) compared with FLOT alone in patients with resectable gastric or gastroesophageal ...
In the experimental arms, patients were randomized to receive a 1500 mg fixed dose of Imfinzi with or without tremelimumab 75 mg every four weeks for 4 cycles each, followed by Imfinzi every four ...
Based on NIAGARA Phase III trial results which showed a 32% reduction in the risk of recurrence and a 25% reduction in the risk of death vs. neoadjuvant chemotherapy alone AstraZeneca’s IMFINZI ...
For patients weighing at least 30 kilograms, according to the regulatory agency, the recommended dose of Imfinzi is 1,500 milligram every three weeks in combination with chemotherapy prior surgery.
and AstraZeneca's anti-PD-L1 immune checkpoint inhibitor Imfinzi ® (durvalumab) in the treatment of late-stage pancreatic cancer ("DURIPANC”). Several subjects from Phase 1 who received the highest ...
In the experimental arms, patients were randomised to receive a 1500mg fixed dose of Imfinzi with or without Imjudo 75mg every four weeks for up to four doses/cycles each, followed by Imfinzi every ...
Patients were randomly assigned to receive a 1500 mg fixed dose of Imfinzi with or without Imjudo 75 mg every four weeks for up to four doses/cycles each, followed by Imfinzi every four weeks for up ...
Imfinzi is given by a health care professional in a hospital or clinic. It is given as an infusion into a vein (intravenously). It usually takes about an hour to receive your dose of Imfinzi.
The trial included 820 patients, who were randomly assigned to receive a 1500 mg fixed dose of Imfinzi plus chemotherapy or placebo plus chemotherapy every three weeks for four cycles prior to surgery ...