Some natural immunity elements play a role in the development of pulmonary fibrosis, and macrophages are among them. At first, they prevent lung injury by encouraging inflammation and attracting ...

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Mechanistically, IL-33 could induce M2 polarization by activating p38-GATA-binding protein 3 signaling. IL-33 combined with anti-CSF1R or p38 inhibitor to regulate tumor-associated macrophages (TAMs) ...

The M2 macrophages were separated from the culture plate with cell ... mTOR signaling participates in angiogenesis promotion induced by M2-EXO As discussed by recently published research, VEGF ...

By contrast, ‘alternatively activated’ M2 macrophages, polarized with IL-4 ... Next, we addressed whether the shift towards pro-inflammatory responses was induced by either IL-4 or IL-13 alone, or was ...

blocked the MSM-induced Arg1 expression in this disease model. MSM protects against MRSA infection through immunomodulation. MSM promotes the expression of Arg1 by lactate-H3K18la pathway to control ...

We sought to determine whether Olfr78 on bone marrow–derived macrophages (BMDMs) senses tumor-derived lactate and mediates lactate-induced M2 polarization. To strengthen our study of the role of ...

A small molecule MIF antagonist attenuated tumor-induced macrophage M2 polarization coinciding with a reduced angiogenic potential (156). Monocyte-derived macrophages respond to a variety of stimuli ...

Here, we analyzed whether Trx-1 might exert atheroprotective effects by promoting macrophage differentiation into the M2 anti-inflammatory phenotype. Trx-1 at 1 μg/mL induced downregulation of p16 ...