This study provides useful information on the impact of Lamin A/C knockdown on gene expression using RNA-Seq analysis. In addition, the impact of Lamin A/C knockdown on telomere dynamics is explored ...

Transwell assay showing increased invasion in SNB19 and U251 glioma cells transfected with FAM111B-overexpressing lentivirus, compared to controls. Magnification ×20 Study shows FAM111B overexpression ...

This study presents an important finding on the role of GATA4 in aging and OA-associated cartilage pathology. The evidence supporting the conclusions is compelling, with rigorous in vitro and in vivo ...

Wacker Biotech US, a CDMO, and Expression Manufacturing, which specializes in viral vector technology, agreed to collaborate to advance the development and manufacturing of lentiviral-based gene ...

In this study, lentiviral vector–transduced autologous CD34 ... blood mononuclear cells and sustained CD18 neutrophil expression of at least 10% of the normal expression as determined by ...

Lentiviral vector (LV)–based gene therapy using CD34+ hematopoietic stem cells (HSCs) demonstrated stable factor VIII expression in severe hemophilia A patients, with higher vector copy numbers ...

These include unpredictable initial levels of expression, a progressive drop ... In his editorial, Mahlangu noted that "the use of lentiviral vector to deliver the factor VIII gene therapy not ...

Gene therapy for hemophilia A with the use of lentiviral vector–transduced autologous HSCs resulted in stable factor VIII expression, with factor VIII activity correlating to vector copy number ...

In a recent study published in the Biotechnology Journal, a team of researchers from Brazil constructed a lentivirus vector with expression specific for mammary glands and carrying the gene for ...

The LV Edge Packaging System has recently been launched to improve cost efficiency and reduce the supply chain risk of lentiviral production ... tunable transgene expression in the transduced ...