Researchers from Waters and Biospring studied the contribution of nucleotide type and modifications on the retention and resolution of 22–24 nt long oligonucleotides in different chromatographic ...

RNA molecules are single stranded polymers made up of RNA nucleotide monomers. Although there are a number of types of RNA, the 3 main forms are messenger RNA (mRNA), ribosomal RNA (rRNA) and transfer ...

The synthesis of PNA involves solid-phase synthesis techniques, where each nucleotide monomer is added one at a time to the ... Peptide nucleic acids (PNAs) are synthetic mimics of DNA or RNA, where ...

The most abundant is the methylation on the N6-position of the RNA-nucleotide adenosine (m6A). It allows the cell to quickly respond to environmental changes by initiating appropriate cellular ...

Users may need to generate IDT notation for modified RNA to be able to order this kind ... is included into nucleotide, otherwise standard phosphate (P) is implied. For monomers having multiple IDT ...

Users may need to generate IDT notation for modified RNA to be able to order this kind of molecules through IDT web site. This task dedicated to the export of presets with defined subunits. Base - ...

The AON is complementary to a specific region of the target RNA that includes the target adenosine. Importantly, the nucleotide in the AON that is opposite the target adenosine contains a deoxyribose ...

The structure suggests how nucleotide monomers might line up to form covalently ... to one another not by phosphodiester bonds, as in RNA and DNA oligomers, but by weak molecular interactions ...

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