Myasthenia gravis (MG) is a rare, chronic autoimmune disorder that disrupts the communication between nerves and muscles. It typically leads to symptoms such as muscle weakness, drooping eyelids, ...

Background IBD is a chronic inflammatory condition driven by complex genetic and immune interactions, yet preclinical models often fail to fully recapitulate all aspects of the human disease. A ...

For the practicing dermatologist, Th1 cells mediate contact dermatitis, Th2 cells mediate atopic dermatitis, and Th17 cells mediate psoriasis. While this is an oversimplification, it is useful for ...

"CD4+ T cells can exist in a naive or memory state, can exhibit polarization to a Th1, Th2, Th17, or Tfh phenotype, or can be regulatory T cells," says lead author of the study Yoshiaki Yasumizu.

Additional findings from cutaneous transcriptome analysis showed that JAK inhibition with abrocitinib was modulating Th1-, Th2-, Th17-, and Th22-mediated pathways in both groups of patients.

Several types exist, including TH1, TH2, TH17, and Treg cells, each with slightly different roles and functions. However, they all work together to help protect the body from foreign pathogens.

Among these immune cells, Th2 cells have long been considered the primary culprit in the development of asthma. However, the role of Th1 and Th17 cells as a friend or a foe in asthma has long been ...

Non-Th2-driven obesity-linked asthma has also been reported, with neutrophilic preponderance and hallmark increases in Th1 and Th17 cells. Obesity is also related to other conditions, including ...

The body’s helper T cells, which help protect against infection but also become overactive in autoimmune disease or allergies, can be grouped into three classes: TH1, TH2, and TH17 cells. Scientists ...

The body’s helper T cells, which help protect against infection but also become overactive in autoimmune disease or allergies, can be grouped into three classes: TH1, TH2, and TH17 cells. Scientists ...