May 16, 2022 · Cardiac shunts are irregular patterns of blood flow in your heart. They’re often genetic, although some are linked to pregnancy factors. Shunt symptoms vary widely.

Aug 31, 2023 · Transcatheter atrial shunt therapies, designed to dynamically lower left atrial (LA) pressure by shunting blood into the larger reservoir of the right atrium and central veins, have been developed as a novel treatment for heart failure (HF) over the past 10+ years.

Compared with pharmacological therapies, atrial shunts have the theoretical advantages of (1) not causing dehydration, kidney injury, or electrolyte imbalances; (2) not lowering blood pressure or causing orthostatic hypotension; (3) avoiding polypharmacy (which is common in HFpEF and associated with adverse outcomes) 6; and (4) producing less ...

The APTURE shunt system allows left atrial decompression through the coronary sinus, preserving the septum for future interventions, minimizing risk of right-to-left shunting and maintaining right atrial flow dynamics.

The creation of an atrial shunt is a novel approach for the management of heart failure. For many patients, a principal determinant of symptoms and impaired functional capacity is elevation in left atrial pressure, which may be considered a “final common pathway” for …

Corvia Medical has conducted multiple REDUCE LAP-HF studies to evaluate the Corvia Atrial Shunt system for the treatment of elevated left atrial pressure in patients with HF.

May 23, 2022 · Atrial shunt device for heart failure with preserved and mildly reduced ejection fraction (REDUCE LAP-HF II): a randomised, multicentre, blinded, sham-controlled trial. Lancet . 2022;399:1130–1140. doi: 10.1016/S0140-6736(22)00016-2

The Corvia Atrial Shunt is a novel, minimally invasive cardiac implant for patients suffering from Heart Failure with Preserved Ejection Fraction (HFpEF) or Mildy Reduced Ejection Fraction (HFmrEF).

The creation of an interatrial shunt has emerged as a new therapy to decompress the left atrium in patients with acute and chronic left heart failure (HF). Current data support the safety of this therapy, and promising preliminary efficacy results ...

Sep 23, 2024 · Transcatheter implantation of an interatrial shunt may be beneficial in patients with HF with reduced LVEF, markedly reducing adverse cardiovascular events (especially HF hospitalizations) in this high-risk cohort not responding to other therapies.