2 days ago · The meaning of SAGO SPLEEN is a spleen which is affected with amyloid degeneration and in which the amyloid is deposited in the Malpighian corpuscles which appear in cross section as gray translucent bodies resembling grains of sago.

Oct 1, 2012 · Deposition of pink amorphous material (amyloid) limited either to germinal follicles (sago spleen) or splenic sinusoids and surrounding connective tissue (lardaceous spleen)

May 14, 2017 · Sago spleen: Amyloid deposits primarily involve the splenic white pulp producing tapioca like granules on gross inspection.

Apr 1, 2025 · Splenic amyloidosis is the extracellular deposition of amorphous insoluble fibrillar proteinaceous content in the spleen and is rarely seen as an isolated entity 1. Most often, it is associated with either systemic amyloidosis or hepatic amyloidosis 1.

Sep 7, 2016 · Normal spleen (left) and splenic hamartoma (right). H&E stain. (WC) Sections show unremarkable splenic parenchyma. The nodules of white pulp are well-spaced and have germinal center formation. The red pulp has a normal vascularity and does not appear to be expanded. No nuclear atypia is apparent.

Sep 26, 2016 · Sago spleen of amyloidosis. Here the amyloid is deposited in Malphigian corpuscles of spleen which in cut section appear as transluscent bodies similar to sago grains and hence the name “sago spleen”

In 1639, Nicholas Fontanus observed an abscess in the liver and white stones in the spleen in the autopsy of a man. This might have been the first case of sago spleen amyloidosis, a form of amyloid deposition in the spleen and the discovery of amyloids [ 30 , 31 ].

Apr 3, 2019 · Sago spleen has a gray, waxy, nodular appearance and is mild to moderately enlarged, and histologically, white pulp (follicles) is affected. If amyloid deposits grow, they replace the white pulp. Lardaceous spleen shows a diffuse waxy appearance and moderate to marked enlargement.

Meaning of sago spleen medical term. What does sago spleen mean?

Special stain on gross – Lugol’s iodine imparts mahogany brown color to the amyloid in tissue. On further adding dilute sulphuric acid it turns blue.