Meet the PDRC Research Team! - University of California, San Diego
Ulupi Jhala, PhD. Dr. Jhala is an Associate Adjunct Professor at UC San Diego's Department of Pediatrics. The Jhala lab has two parallel research interests. The first is focused on …
Ulupi JHALA | University of California, San Diego, California
Ulupi JHALA | Cited by 4,997 | of University of California, San Diego, California (UCSD) | Read 35 publications | Contact Ulupi JHALA
Ulupi Jhala - Google Scholar
UCSD - Cited by 6,015 - diabetes
Ulupi Jhala - Assoc Res Professor - UCSD | LinkedIn
View Ulupi Jhala’s profile on LinkedIn, a professional community of 1 billion members. Assoc Res Professor at UCSD · Experience: UCSD · Location: San Diego County · 56 connections on …
- Title: Assoc Res Professor at UCSD
- Location: UCSD
- Connections: 56
Basic & Translational Research Programs - University of California, …
Dr. Ulupi Jhala's lab is focused on understanding signaling mechanisms that modulate the progression of beta cell inflammation, a critical turning point in the development of type 1 …
Mechanisms of Pancreatic Beta Cell Dysfunction - Ulupi Jhala
Jul 1, 2019 · We propose the following specific aims: 1) Examine how mice with whole body and beta cell-specific loss of TRB3, response to induced diabetes. 2) Examine the role of TRB3 …
Nutrient regulation of the islet epigenome controls adaptive …
Apr 17, 2023 · Here, we have shown that nutrient-stimulated histone acetylation plays a key role in adapting insulin secretion through regulation of genes involved in β cell nutrient sensing and …
Sirt1 Regulates Insulin Secretion by Repressing UCP2 in Pancreatic …
We show that Sirt1 positively regulates insulin secretion in pancreatic β cells. Sirt1 represses the uncoupling protein (UCP) gene UCP2 by binding directly to the UCP2 promoter. In β cell lines …
CREB regulates hepatic gluconeogenesis through the coactivator …
Sep 13, 2001 · Here we show that mice carrying a targeted disruption of the cyclic AMP (cAMP) response element binding (CREB) protein gene, or overexpressing a dominant-negative …
Characterization of a CREB Gain-of-Function Mutant with …
Here we characterize a Tyr134Phe CREB mutant that behaves as a constitutive activator in vivo. Like protein kinase A (PKA)-stimulated wild-type CREB, the Tyr134Phe polypeptide was found …