F(ab')2, Fab, Fab' and Fv are antigen-binding fragments that can be generated from the variable region of IgG and IgM. These antigen-binding fragments vary in size (MW), valency and Fc …

The fragment crystallizable region (Fc region) is the tail region of an antibody that interacts with cell surface receptors called Fc receptors and some proteins of the complement system. This …

Each half is made up of a heavy chain of approximately 50 kDa and a light chain of approximately 25 kDa, joined together by a disulfide bond near the carboxyl terminus of the light chain. The …

Dalton (Da) is an alternate name for the atomic mass unit, and kilodalton (kDa) is 1,000 daltons. Thus a protein with a mass of 64 kDa has a molecular weight of 64,000 grams per mole

The Fc-fusion-tag allows simple and efficient affinity purification of the tagged protein using protein A or protein G affinity chromatography. The Fc-fusion-tag (Fc-chimeric) also can be …

Overlay of molecular weight (MW) standard (gel filtration standard, Bio-Rad) is shown as red line: 670 kDa (thyroglobulin), 158 kDa (γ-globulin), 44 kDa (ovalbumin), 17 kDa (myoglobin), and …

Through Fab or Fc engineering, IgG-FcRn interaction can be used to generate a variety of therapeutic antibodies with significantly enhanced half-life or ability to remove unwanted …

Jan 25, 2018 · What is the molecular weight (mw) of Immunoglobulin G (IgG)? 150 kDa. While the molecular weight of IgG varies depending on the species, the typical value cited is 150,000 …

Fc intermediate (Fci) is a papain-generated fragment of human IgG which is intermediate in charge, mol. wt and state of cleavage between the Fc and Fc' fragments of IgG. It is …