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SOLVED: If a patient is a heterozygote for Rb, which of the followingwould result in loss of heterozygosity?I. Mitotic recombinations that results in a daughter cell withtwo mutant copies of RbII. Chromosomal nondisjunction during mitosis resulting in adaughter cell with an extra mutant chromosome, followed by the lossof the WT chromosome in subsequent mitosis.III. Methylation of the Rb promoter resulting in inactivation ofRb function.
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