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Mechanism of action of opioids

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Mechanism of action of opioids

Opioid agonists produce analgesia by binding to G protein-coupled receptors (GPCRs) in the brain and spinal cord regions involved in the transmission and modulation of pain Opioid drugs mimic endogenous compounds: endorphins, enkephalins, and dynorphins that bind to opioid receptors. Four opioid receptor types: mu (μ), kappa (κ), delta (δ ...

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Opioids, Inc. (full documentary) | FRONTLINE

Opioids, Inc. (full documentary) | FRONTLINE

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Fentanyl: The Drug's Toll on Users, First Responders and the Law

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This Mysterious Drug Can Erase Addiction ‘Virtually Overnight’ | WSJ

This Mysterious Drug Can Erase Addiction ‘Virtually Overnight’ | WSJ

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